Last updated on December 28, 2015

Sources of Hazard Information

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  • Definitions of the symbols,X and Y, in relation to the GHS Classification Guidance and Chemical Substances Control Law are as described below.
    • X: List 1 (GHS Classification Guidance) or Priority 1 (CSCL)
    • Y: List 2 (GHS Classification Guidance) or Priority 2 (CSCL)
Please click here [Japanese] for the details regarding the order of priority of information sources.

* Click here [Japanese] for the Descriptions of Information Sources Regarding Human Health Hazards

Country, Region, etc. Organization Information Source Order of priority in terms of GHS Classification Guidance Order of priority in terms of CSCL Screening Assessment Presence of Hazardous Properties Presence of Key Study [Reference] Presence of link with NITE CHRIP
Human health hazards Aquatic environmental hazards Human health Ecological effects General toxicity Reproductive and developmental toxicity Mutagenicity
JapanMinistry of the Environment (MOE)Environmental Risk Assessment of Chemicals and Ecological Risk Assessment of ChemicalsXXXXXXXX
Ecological effect study of ChemicalsXX
Registration Withholding Standards of Agricultural Chemicals concerning Prevention of Damage to Aquatic Animals and PlantsX
Ministry of Health, Labour and Welfare (MHLW)Japan Existing Chemical Data Base (JECDB)XXXXXX
Publications of the guidelines for preventing the impairment of workers' health, according to the provision of paragraph (3) of Article 28 of the Industrial Safety and Health ActXX
Studies on safety evaluation of existing food additives (2006)YXXXX
Ministry of Economy, Trade and Industry (METI) and NITE (National Institute of Technology and Evaluation)NITE J-CHECK (Hazard information collected under the Japan Challenge Program, toxicity data evaluated by CSCL screening, etc.)XXXXXX
METI, MHLW, and MOEHazard data evaluated by CSCL screening (Expert Committee on Chemical Substances in the Environmental Health Committee of the Central Environment Council)XXXXX
NITE, CERI (Chemicals Evaluation and Research Institute)Initial Risk Assessment Reports of Chemical Substances (NITE/CERI)XXXXXXXXX
Inter-Ministerial Meeting on GHS and MHLW (Japan Industrial Safety and Health Association)GHS Classification Results by the Japanese GovernmentXXXXX
Food Safety Commission of JapanAssessment of the effect of food on healthYXXXXX
Japan Society for Occupational Health (JSOH)Recommendation of Occupational Exposure Limits (OELs) and the Statement of Reasons for the Recommendation
(Updated on July 24, 2015)
XXXXX
Japan Bioassay Research CenterResults of carcinogenicity studies commissioned by MHLWXXX
Food and Agricultural Materials Inspection CenterAgricultural chemical summaries and assessment reportsYYXXX
Japan Crop Protection AssociationPesticide Safety InformationYYX
Others (Japanese domestic standards)Standard values based on Japanese laws
Drinking Water Quality Standard (Updated on May 21, 2015);
Environmental Quality Standards for Water Pollution;
Guideline Values of items for precautionary monitoring for Water Pollution;
Environmental Quality Standards for Air Pollution;
Guideline Values for Air Pollutants;
Temporary ADI for Inedible Agricultural Chemicals (Database of ADI-related information for Agricultural Chemicals)
XX
International OrganizationsOECDSIDS Initial Assessment Report (SIDS Report)XXXXXXXX

X

SIAP:
999 substances
SIAP+SIAR:
1203 substances

eChemPortalXXXXXXX
WHO/IPCS (International Programme on Chemical Safety)EHC (Environmental Health Criteria)
(Updated on May 21, 2015)
XXXXXXXXX
CICAD (Concise International Chemical Assessment Documents)XXXXXXXXX
WHO/IARC (International Agency for Research on Cancer)IARC Monographs on the Evaluation of Carcinogenic Risk to HumansXXXX
WHO/FAO (Food and Agriculture Organization of the United Nations)PDSs (Pesticide Data Sheets)
(Updated on July 24, 2015)
X
FAO/WHO JECFA (Joint Expert Committee on Food Additives)JECFA Monographs (FAO/WHO Joint Expert Committee on Food Additives - Monographs)XXXXXX
FAO/WHO JMPR (Joint Meeting on Pesticide Residues)JMPR Monographs (FAO/WHO Joint Meeting on Pesticide Residues - Monographs of toxicological evaluations (pesticide residues))XXXXXX
WHOGuidelines for drinking-water qualityXX
Air Quality Guidelines for Europe
(Updated on May 21, 2015)
XX
EUEU ECB (European Chemicals Bureau)EU RAR (EU Risk Assessment Reports)XXXXXXXXX
EU ECHAREACH Registered substances
C&L (Classification & Labelling) Inventory database
SVHC (Candidate List of Substances of Very High Concern)X
CoRAP (Community Rolling Action Plan) list of substances
ECETOCTechnical Report Series and JACC Report SeriesXXXXXXX
TR 091: ECETOC Aquatic Toxicity (EAT) databaseX
German Chemical Society-Advisory Committee on Existing Chemicals (BUA) of Environmental RelevanceBUA Report (BUA)
(Updated on May 21, 2015)
YYYXXXX
DFG (Deutsche Forschungsgemeinschaft)MAK Collection for Occupational Health and Safety, MAK Values Documentations and the List of MAK and BAT valuesXXXXXX
IFA (Institut fur Arbeitsschutz der Deutshen Gesetzlichen Unfallversicherung)GESTIS DNEL Database
United StatesEPA (Environmental Protection Agency)Integrated Risk Information System (IRIS)XXXXXXX
US HPV Challenge Program (HPV-IS) (only those evaluated by EPA)XXXXXX
Aquatic Toxicity Information Retrieval (AQUIRE)Y
EPA Water Quality CriteriaXX
Pesticides Reregistration Eligibility Decision (RED)XXXXXXXX
Pesticide Ecotoxicity DatabaseX
NTP (National Toxicology Program)NTP Database Search Home Page
(Updated on May 21, 2015)
XX
Report on Carcinogens (RoC) (12th, 2011)
(Updated on April 1, 2015)
X
Technical reports of long-term carcinogenesis studies
(Updated on April 1, 2015)
XX
ACGIH (American Conference of Governmental Industrial Hygienists)ACGIH Documentation of the threshold limit values for chemical substances (7th edition, 2001) (2012 supplement, 2012) and TLVs and BEIs (issued annually)
(Updated on June 19, 2015)
XXXXXX
ATSDR (Agency for Toxic Substances and Disease Registry)Toxicological ProfilesXXXXXXX
NLM (National Library of Medicine)Hazardous Substance Data Bank (HSDB)YYXXX
CanadaEnvironment Canada, Health CanadaAssessment Report of Environment Canada: Priority Substance Assessment ReportsXXXXXXXX
AustraliaNICNASPriority Existing Chemical (PEC) Assessment ReportsXXXXXXXX
OthersE. Bingham, B. CohrssenPatty’s Toxicology (6th edition, 2012) (Patty)XXXXXX

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CSCL Individual Substance Information

CSCL Screening Assessment Results

Web pages on reliability evaluation of physicochemical properties and hazard data according to the CSCL

http://www.meti.go.jp/policy/chemical_management/kasinhou/information/shinraisei_kijun.html

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Information on the Information Sources

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Information Sources on the GHS Classification Guidance (Inter-Ministerial Meeting on GHS)

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Information on Exposure Assessment

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Regulatory Information

regulatory information

Country, International Organization Name of the law How to access the information
United NationsUN Number and UN Hazard ClassUN Numbers and Hazard Class are indicated in the PDF file “Part 2: Classification”
EUREACH: Substances of Very High Concerns (SVHC)-
United StatesToxic Substances Control Act (TSCA): Significant New Use Rules (SNUR)Select “TSCA 5A SNUR (1820) - Significant New Use Rules” from the search list and press the Search button at the bottom of the page. Although a message appears, stating that the search results were too large to display, click “Export Core Metadata for List” or "Export List Information" under Export Options below to download a substance list in CSV format.
United StatesToxic Substances Control Act (TSCA): Regulation of hazardous chemical substances and mixturesSelect “TSCA 6 Unreasonable Risk (25) - Hazardous Chemicals Control Rules” from the search list and press the Search button at the bottom of the page to show the list. The list can be downloaded in Excel and CSV format.
South KoreaToxic Chemicals Control ActFive substance lists are displayed and can be downloaded in Excel format. The lists include (from the top): the list of hazard assessment results for existing chemicals, the list of GHS classification and labelling, the list of toxic chemical substances, the list of observational chemical substances, and the list of chemicals excluded from Toxic substances.
VietnamLaw on Chemicals (Law No. 06/2007/QH12)List of substances determined by Decree No. 108/2008/ND-CP of Vietnamese Law on Chemicals (Law No. 06/2007/QH12) is available in PDF file on ECOLEX and can be accessed from “Link to full text: vie84416.pdf” in the middle of the page. When the decree is updated, a link to the updated version will be provided at “Amended by:” under References. (The newest version is “Decree No. 26/2011/ND-CP,” although the substance list has not been updated.)
IndonesiaGovernment Regulation No.74/2001 on Management of Hazardous and Toxic Substances(Coming soon)
ThailandHazardous Substances Act (Jurisdiction of the Ministry of Industry, Department of Industrial Works)(Coming soon)
OECDHigh Production Volume (HPV) ChemicalsIn the OECD Existing Chemicals Database, select “By HPV chemical only” in the third box from the top on the right side of the page. Click the Search button to display the HPV chemicals list.
ICCAHigh Production Volume (HPV) ChemicalsThe list of HPV chemicals by ICCA is available. Select “ICCA HPC Working List” under “The latest publication” at the bottom of the page to browse the list in PDF format.
-Stockholm Convention on Persistent Organic Pollutants (POPs)The substance lists in Annexes A, B, and C are available.
-Rotterdam Convention on the Prior Informed Consent (PIC)The substance list in Annex III of PIC Convention is available.

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GHS Information

GHS Information

Country Organization Name Description
South KoreaKOSHA (Korea Occupational Safety and Health Agency)GHS classification results of more than 10,000 substances can be viewed in the GHS information database by KOSHA (Korea Occupational Safety and Health Agency)
National Institute of Environmental Research
(Updated on February 26, 2015)
Database on GHS classification information on the website of National Institute of Environmental Research. Search is possible at BIGDr’s Chemical Hazard Database Portal.
TaiwanCLA (Council of Labor Affairs) (Updated on February 26, 2015)GHS classification results and SDS of 3,171 substances can be viewed in the GHS information database by Taiwan CLA
Taiwan EPA (Environmental Protection Administration Executive Yuan, R.O.C.) (Updated on February 26, 2015)GHS, SDS, prevention, and relief manuals are summarized by substance on the website of Taiwan EPA. Press the GHS SDS button of each substance to display the contents in a Word file.
National Taipei University of Technology (Updated on February 26, 2015)GHS information can be searched on the website of Taipei Tech. Select “All” in the search box and press “Inquiry” to display the substance list. In addition, search by substance name and CAS Number is also possible.
ThailandDepartment of Industrial Works of the Ministry of IndustryGHS classification results of 525 substances can be viewed in the GHS Information database by the Department of Industrial Works of Ministry of Industry in Thailand
MalaysiaDepartment of EnvironmentGHS classification results of 3,843 substances can be viewed in the EHS (Environmentally Hazardous Substances) database of the Malaysian Department of the Environment.

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Disclaimer

Disclaimer

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